文献综述附子炮制品的炮制机理及化学成分研究进展摘要：附子为毛茛科植物乌头的子根加工品，始载于《神农本草经》，是临床常用的温里药之一，具有回阳救逆，补火助阳，温通经脉之效。
但由于附子有大毒，需经炮制减毒后方可内服，不同的炮制方法对其药效药性及毒性的均有影响。
其主要有效成分是形式多样的乌头类生物碱。
本文就附子的炮制及炮制品的炮制机理及化学成分研究进展作如下综述。
关键词：附子炮制品生物碱炮制方法ABSTRACT: Aconitum Root Processing Product of Ranunculaceae plant, which was first published in Shennong Herbal Medicine Classic, is one of the commonly used warming medicine in clinic. It has the effect of rejuvenating Yang and relieving adversity, supplementing fire and yang, warming and dredging meridians. However, due to its toxicity, aconite can be taken orally only after being processed and attenuated. Different processing methods have effects on its pharmacodynamics and toxicity. Its main active ingredient is aconitine alkaloids in various forms. In this paper, the processing mechanism and chemical constituents of aconite and its processed products are summarized as follows.Key word: Alkaloid constituents Processing method1.来源、采收加工及历史沿革附子为毛茛科植物乌头Aconitum carmichaelii Debx.的子根加工品[1]。
6月下旬至8月上旬采挖，除去母根、须根及泥沙，习称泥附子。
或选择个大、均匀的泥附子，洗净，浸入食用胆巴的水溶液中过夜，再加入食盐，继续浸泡，每日取出晾晒，并逐渐延长晾晒时间，直至附子表面出现大量结晶盐粒（盐霜）、体质变硬为止，习称盐附子。
汉代有炮法；晋代有制炭法；南北朝刘宋时代有东流水并黑豆浸法；唐代有蜜涂炙、纸裹煨等法；宋代有水浸、姜煮、姜汁淬、醋浸、烧炭存性、盐汤浸炒、姜汁巴豆煮、盐泔水煮、盐水炒、盐姜煮、甘草汤炒、麸炒、炒等方法；清代又有甘草煎、蒸等法。
现行有蒸制、煮制、砂炒等。
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