LU201701对慢性轻度应激抑郁模型的治疗作用文献综述

 2023-03-03 22:09:26

抑郁症动物模型的研究进展

摘 要:抑郁症是一种慢性、易复发、可能危害生命的全球性疾病。尽管抑郁症发病具有很高的普遍性,但其发病机制至今尚未清楚,而有效的实验动物模型为探索抑郁症的病理、病因及可能的治疗方案拓宽了思路。本文归纳总结了药理学研究中常用抑郁症动物模型的研究进展,以期为开展抑郁症发病机理研究及其临床治疗药物的研制提供参考。

关键词:抑郁症;疾病;动物;动物模型

Research progress on animal models of depression

(Pei Yang, Nanjing University of Chinese Medicine, 047113353)

[Abstract]Depression is a chronic, recurring and potentially life-threatening global disease. Although the incidence of depression has a high prevalence, its pathogenesis is not clear. However, the effective experimental animal model was a powerful tool to clarify the pathology and etiology of depression and further establish its possible therapeutic regimen. In this paper, research progresses on animal models of depression usually used in pharmacology were summarized to provide some references for the study on the mechanism of depression and the development of its therapeutic drugs.

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